Tumori neuroendocrini dell'apparato digerente: Diagnosi dalla A alla Z
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In pratica, si distingue tra tumori endocrini del tratto digestivo, tumori endocrini pancreatici e tumori endocrini epatici. Le circostanze in cui questi tumori vengono scoperti variano, in particolare a seconda che siano funzionali o meno.
La sindrome da carcinoide è la manifestazione clinica caratteristica di questi tumori. È causata dal rilascio di serotonina e di altri peptidi (bradichinina, istamina, sostanza P, ecc.
) da parte del tumore. Si verifica solo nel 10-20% dei pazienti, soprattutto in presenza di metastasi epatiche.
È tipicamente associata a vampate di calore e diarrea motoria. La cardiopatia da carcinoide può essere presente dopo un lungo periodo di evoluzione in circa un terzo dei casi.
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£27.18
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