Health, Family & Lifestyle      Medical & Healthcare Practitioners

TRAITEMENT DE L'INFECTION PAR LE VIRUS DE L'HERPÈS SIMPLEX

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Book Details
Language
French
Publishers
Editions Notre Savoir (19 Jun. 2024)
Weight
0.12 KG
Publication Date
19/06/2024
ISBN-10
6207661370
Pages
72 pages
ISBN-13
9786207661374
Dimensions
15 x 0.43 x 22 cm
SKU
9786207661374
Author Name
Akiladevi Durairaj (Author)
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Formulation d'un insert médicamenteux soluble de famciclovir pour une nouvelle administration de médicaments contenant le polymère hydrophile naturel hydroxypropylcellulose et le polymère hydrophobe éthylcellulose en utilisant la méthode de coulée de solvant. Augmentation du temps de contact, libération contrôlée, diminution de la fréquence d'administration, amélioration de l'observance par le patient et plus grande efficacité thérapeutique.

La formulation F2 contenant du famciclovir et 4 mg d'hydroxypropylcellulose pris en sandwich entre l'éthylcellulose en tant que polymère répondait aux caractéristiques pharmaceutiques requises pour les inserts oculaires et s'est avérée prometteuse. L'étude de diffusion in vitro a permis de conclure que la formulation F2 présentait une libération supérieure de 98,99 % avec des caractéristiques contrôlées pendant 8 heures par rapport aux autres formulations.

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