Synthèse du (-) – pyrénophorol, évaluation anticancéreuse des hétérocycles: benzimidazole, benzthiazole et dérivés sulfonamides
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Reviews & Ratings
018±0,0039 μM, A549 = 0,011±0,0019 μM, Colo-205 = 0,12±0,029 μM et A2780 = 0,17±0,023 μM) que l'étoposide. Le composé 117i ayant une partie phényle riche en électrons a montré une plus grande propriété anticancéreuse sur toutes les lignées cellulaires (PC3=0,11±0,068 μM ; A549=0,18±0,063 μM ; MCF-7= 0,52±0,074 μM et DU-145=0,17±0,082 μM).
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