Sulla strada dagli istoni al cromosoma
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Il DNA deve essere disponibile per la formazione del complesso di preiniziazione, con la sua RNA polimerasi e i fattori di trascrizione generali. Sembra che il DNA avvolto intorno ai nucleosomi spesso non sia accessibile per la formazione del complesso di preiniziazione, ma sia disponibile per il riconoscimento da parte delle proteine attivatrici della trascrizione, chiamate anche fattori di trascrizione specifici.
Ci concentriamo sul ruolo degli istoni, sulla loro regolazione e sul rimodellamento della cromatina nell'espressione genica. .
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£27.18
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