Studio dei geni della beta-lattamasi OXA in Acinetobacter Baumannii
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In Iraq c'è poca attenzione sulle basi molecolari della resistenza ai farmaci multipli degli isolati di A. baumannii nei nostri ospedali, pertanto gli obiettivi dello studio sono: Indagare la distribuzione dei ceppi di A.
baumannii multiresistenti ai farmaci (MDR) isolati da pazienti ricoverati e rilevare la presenza dei geni delle β-lattamasi di classe D (blaOXA-23-Like, blaOXA-24-Like, blaOXA- 51-Like e blaOXA-58-Like) negli isolati di A. baumannii e indagare sulla loro distribuzione tra tutti gli isolati clinici.
Analizzare la sequenza dei geni blaOXA per individuare le variazioni degli isolati locali. Correlazione dei geni delle pompe di efflusso con la resistenza ai farmaci e ai carbapenemi.
Misurazione dell'espressione genica dei geni blaOXA più diffusi. .
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£27.18
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