Síntese de (-) - pirenoforol, avaliação anticancerígena de heterociclos: derivados de benzimidazol, benztiazol e sulfonamida
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018±0,0039 μM, A549 = 0,011±0,0019 μM, Colo-205 = 0,12±0,029 μM e A2780 = 0,17±0,023 μM) do que o etoposido. O composto 117i, rico em electrões na porção fenil, apresentou maior propriedade anticancerígena em todas as linhas celulares (PC3=0,11±0,068 μM; A549=0,18±0,063 μM; MCF-7= 0,52±0,074 μM e DU-145=0,17±0,082 μM).
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