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PD-L1 and Hodgkin’s Lymphoma: Immunohistochemical Expression of PD-L1 and EBV in Hodgkin’s Lymphoma

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Book Details
Language
English
Publishers
LAP LAMBERT Academic Publishing (22 Jun. 2024)
Weight
0.2 KG
Publication Date
22/06/2024
ISBN-10
6207806360
Pages
128 pages
ISBN-13
9786207806362
Dimensions
15 x 0.74 x 22 cm
SKU
9786207806362
Author Name
Mohammed Abdulrahman (Author)
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In Hodgkin Lymphoma (HL), immunohistochemical expression of programmed death ligand 1 (PD-L1) is found in 67. 5% of HL cases and 35% of the tumor micro-environment.

However, there is no significant association between PD-L1 expression and the presence of EBV latent membrane protein-1 (LMP-1). Only 29.

6% of patients with positive PD-L1 expression also show positive EBV LMP-1. Additionally, no significant associations were identified between PD-L1 expression and HL subtype, age, and gender.

On the other hand, EBV LMP-1 immunohistochemical expression is significantly associated with male gender (83. 3%) and certain histological subtypes but reveals no statistically significant difference concerning the age of the patients.

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