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Ein direkter Knochenkontakt, wie er histologisch beobachtet wird, kann auf das Fehlen einer lokalen oder systemischen biologischen Reaktion auf diese Oberfläche hinweisen. Es wird daher vorgeschlagen, dass Osseointegration nicht das Ergebnis einer vorteilhaften biologischen Gewebereaktion ist, sondern eher das Fehlen einer negativen Gewebereaktion.
In diesem Buch sollen die grundlagenwissenschaftlichen Arbeiten zum Konzept der Biologie der Osseointegration ausgewertet und die spezifischen Faktoren erörtert werden, die mit der Knochenheilung um ein Implantat herum zusammenhängen können. .
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