Nuovo approccio al trattamento del virus dell'epatite C di genotipo 4
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Sofosbuvir è un analogo nucleotidico pirimidinico ad azione diretta, il primo inibitore della polimerasi NS5B dell'HCV. Ha una potente attività contro tutti i genotipi di HCV.
Il sistema immunitario innato rappresenta la prima linea di difesa dell'ospite contro gli agenti patogeni. Le modalità di trattamento con Sofosbuvir più ribavirina o Sofosbuvir più ribavirina e interferone pegilato sono altamente efficaci nei pazienti infettati dal genotipo 4 dell'HCV.
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