Nuova via per la sintesi di 1,2,4-ossadiazina-5-oni chirali: Facile sintesi di nuovi 1,2,4-ossadiazin-5-oni chirali da aminoacidi naturali
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Questi reagiscono poi con cloruro di tionile seguito da metanolo per dare i corrispondenti α-bromoesteri. La condensazione di questi α-bromoesteri precedentemente preparati con 1-benzensolfonilpirrolidina-2-carbossamidossima in presenza di due equivalenti di idruro di sodio ha permesso di ottenere i nuovi 1,2,4-ossadiazin-5-oni chirali desiderati in buone rese chimiche.
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£27.18
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