Nouvelle approche du traitement du génotype 4 du virus de l'hépatite C
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Le sofosbuvir est un analogue de nucléotide pyrimidine à action directe, le premier inhibiteur de la polymérase NS5B du VHC. Il a une activité puissante contre tous les génotypes du VHC.
Le système immunitaire inné représente la première ligne de défense de l'hôte contre les agents pathogènes envahissants. Les modalités de traitement par Sofosbuvir plus ribavirine ou Sofosbuvir plus ribavirine et interféron pégylé sont très efficaces chez les patients infectés par le génotype 4 du VHC.
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