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Non-traditional Approaches to Combat Antimicrobial Drug Resistance

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Book Details
Language
English
Publishers
Springer; 1st ed. 2023 edition (16 Feb. 2024)
Weight
0.47 KG
Publication Date
29/02/2024
ISBN-10
9811991693
Pages
333 pages
ISBN-13
9789811991691
Dimensions
15.5 x 1.93 x 23.5 cm
SKU
9789811991691
Author Name
Mohmmad Younus Wani (Editor)
Dr. Wani is an associate professor of organic and medicinal chemistry at the University of Jeddah, Saudi Arabia. His research focuses on developing new small-molecule inhibitors and innovative strategies to combat antimicrobial resistance (AMR). With over a decade of research and teaching experience, Dr. Wani has authored over 60 peer-reviewed research articles, six books, and several US patents. Dr. Wani is recognized for his contributions in this critical field. His work addresses one of the top 10 global public health threats identified by the World Health Organization. Dr. Wani's expertise bridges chemistry and biology, driving progress in the fight against AMR and advancing key issues of the 21st century.Read more about this authorRead less about this author
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This book provides a detailed overview of the progress and challenges of non-traditional approaches for tackling antimicrobial resistance. The first chapter covers the factors that make microbes more likely to develop multidrug resistance.

The book goes on to discuss the antimicrobial properties of propolis, essential oils and other microbial constituents that are used or under investigation to treat multidrug-resistant infections. Additionally, it covers alternative compounds that work as antimicrobial agents, their mechanisms of action, and how they might be utilized in conjunction with conventional drugs to circumvent drug resistance.

The book explores the application of phage therapy and recent advancements in phage-based infection control with an emphasis on multidrug-resistant infections and discusses drug repurposing as a strategy to develop new antimicrobial agents efficiently and expeditiously. Additionally, it discusses the uses of nanoparticles in the treatment of infectionsbrought on by multidrug-resistant pathogens and examines the use of different nanotechnology-based approaches to fudge microbial resistance mechanisms.

It concludes by reviewing recent studies on microbial quorum-sensing systems and focuses on the significance of quorum-sensing systems in controlling microbial resistance mechanisms and at the same time highlights the importance and role of antimicrobial stewardship program to fight microbial infections. The book is an invaluable source of knowledge and information for academics, basic and clinical researchers, clinicians, and paramedic staff involved in one way or the other in the development and use of antimicrobial agents and strategies to combat multidrug resistance.

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