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Feynman de "muito espaço no fundo" na década de 1950 até à criação do termo "nanotecnologia" por K. Eric Drexler na década de 1980.
O impacto da nanotecnologia na medicina é multidimensional, abrangendo a regeneração de tecidos, a administração de medicamentos, os biossensores, a transfecção de genes e a imagiologia. Esta influência é atribuída principalmente às propriedades distintivas dos nanomateriais, caracterizadas por uma relação superfície/volume melhorada em comparação com os seus homólogos macro.
À escala nanométrica, os materiais apresentam comportamentos únicos, o que os torna adequados para uma miríade de aplicações biomédicas. No domínio dentário, o campo florescente da nanodentística tira partido da nanotecnologia para inaugurar uma nova era de cuidados de saúde oral abrangentes.
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