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Par exemple, certaines bactéries peuvent se diviser toutes les neuf minutes. De plus, la chaîne d'ADN ou génome (gee-nome) des microbes est relativement petite.
Par exemple, la bactérie moyenne ne possède qu'environ cinq millions de bases d'ADN. Ainsi, à chaque nouvelle génération de bactéries, il peut y avoir une ou deux erreurs dans le code génétique.
En d'autres termes, ces mutations aléatoires se produisent suffisamment souvent chez les microbes pour jouer un rôle significatif dans leur capacité à survivre et à s'adapter. .
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