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Por exemplo, algumas bactérias podem dividir-se a cada nove minutos. E toda a cadeia de ADN ou genoma (gee-nome) dos micróbios é relativamente pequena.
Por exemplo, uma bactéria média tem apenas cerca de cinco milhões de bases de ADN. Assim, em cada nova geração de bactérias, pode haver um ou dois erros no código genético.
Por outras palavras, estas mutações aleatórias ocorrem com frequência suficiente nos micróbios para desempenharem um papel significativo na sua capacidade de sobrevivência e adaptação. .
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