Microgenomica delle lesioni odontogene: Patologia molecolare
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Meccanismi molecolari incerti sono alla base della comparsa di queste lesioni. Secondo alcuni studi, gli oncogeni o i geni soppressori del tumore possono essere disregolati in alcune lesioni.
La down-regulation del gene P53 è stata documentata in AB, DC e OKC. Anche diversi RNA lunghi non codificanti, tra cui KIAA0125 e ENST00000512916, sono stati disregolati nei tessuti AB.
Numerosi geni contengono polimorfismi a singolo nucleotide che sono stati collegati a specifiche lesioni odontogene. Forniamo una sintesi delle informazioni più recenti sul profilo di espressione genica in queste lesioni e sulla relazione tra i polimorfismi genetici e la comparsa di queste lesioni.
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£27.18
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