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Esta literatura discutirá seletivamente as causas da limpeza das células e as características patológicas dos tumores com alterações das células claras, que, por vezes, podem constituir um desafio e um dilema de diagnóstico. O comportamento biológico pode variar de indolente a agressivo.
Mas, na maioria dos casos, a presença de um tumor de células claras pode ser um sinal de aumento da agressividade e malignidade do tumor. Por conseguinte, a sua designação adequada é fundamental.
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