Science, Nature & Maths      Chemistry

Le nouveau 1,2,3-triazole étiqueté 5-[(1H-Indol-3yl)méthylène]pyrimidine: Composés hétérocycliques

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Book Details
Language
French
Publishers
Editions Notre Savoir (30 Jun. 2024)
Weight
0.13 KG
Publication Date
30/06/2024
ISBN-10
6207741781
Pages
76 pages
ISBN-13
9786207741786
Dimensions
15 x 0.46 x 22 cm
SKU
9786207741786
Author Name
B.ASHOK KUMAR (Author)
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Composé hétérocyclique dans lequel le benzène est fusionné avec un anneau pyrrole. Il a été identifié pour la première fois par Baeyer en 1866 alors qu'il effectuait des recherches sur la structure du colorant naturel indigo.

Le pharmacophore indole est un constituant omniprésent de nombreux produits naturels, dont les hormones végétales (acide indole-3-acétique), certaines hormones animales telles que la mélatonine et la sérotonine et de nombreux alcaloïdes tels que la vinblastine, la vincristine, la vindésine, la vinorelbine, l'ajmaline et la physostigmine. De même, il est le principal composant de plusieurs médicaments synthétiques tels que l'indométhacine, la fluvastatine, le zafirlukast et l'ondansétron.

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