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Influence of Aflatoxin on the phagocytic capacity of neutrophils and mo

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Book Details
Language
English
Publishers
Our Knowledge Publishing (31 May 2024)
Weight
0.09 KG
Publication Date
31/05/2024
ISBN-10
6207608453
Pages
52 pages
ISBN-13
9786207608454
Dimensions
15 x 0.3 x 22 cm
SKU
9786207608454
Author Name
Rodrigo Henrique Pereira P. Santos (Author)
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Aflatoxin is a mycotoxin that can be present in various foods and is a source of poisoning for humans and animals. Patients with aflatoxin poisoning have a worrying degree of morbidity and mortality.

However, little is known about its effects on the human body and how immunopathological processes are triggered. As phagocytosis is a very important mechanism, it is necessary to understand the possibility of it causing immunodepression in the individual.

The aim of this study was to evaluate the influence of aflatoxin on the phagocytic capacity of human neutrophils and monocytes by counting the number of monocytes and neutrophils involved in phagocytosis, the average number of Saccharomyces cerevisiae yeasts phagocytosed and/or adhered and the phagocytic index and superoxide production. The results showed a negative modulation of phagocytosis, both due to a reduction in the yeasts ingested/adhered and the lower number of cells involved.

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