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Nos tempos modernos, atingiu proporções epidémicas . A prevalência da cárie dentária nos países desenvolvidos é muito variável e pode atingir mais de 90%.
Este livro destaca a indução da cárie dentária que envolve múltiplas proteínas de S. Mutans, e servirá de modelo para a preparação de outras construções genéticas a incluir numa vacina dentária combinada.
Os resultados obtidos terão impacto no desenvolvimento futuro de vacinas , não só contra S. mutans, mas também contra outros agentes patogénicos que utilizam o revestimento da mucosa do trato respiratório, gastrointestinal e genito-urinário como via de entrada no hospedeiro.
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