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Nei tempi moderni ha raggiunto proporzioni epidemiche . Laprevalenza della carie dentale nei Paesi sviluppati varia notevolmente e può raggiungere oltre il 90%.
Questo libro evidenzia l'induzione della carie dentale che coinvolge più proteine di S. Mutans e servirà da modello per la preparazione di altri costrutti genici da includere in un vaccino dentale combinato.
I risultati ottenuti avranno un impatto sul futuro sviluppo di vaccini , non solo contro lo S. mutans, ma anche contro altri patogeni che utilizzano la mucosa del tratto respiratorio, gastrointestinale e genito-urinario come via di ingresso nell'ospite.
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