Science, Nature & Maths      Chemistry

Il nuovo 1,2,3-Triazolo Tagged 5-[(1H-Indol-3il)metilene]pirimidina: Composti eterociclici

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Book Details
Language
Italian
Publishers
Edizioni Sapienza (30 Jun. 2024)
Weight
0.12 KG
Publication Date
30/06/2024
ISBN-10
620774179X
Pages
72 pages
ISBN-13
9786207741793
Dimensions
15 x 0.43 x 22 cm
SKU
9786207741793
Author Name
B.ASHOK KUMAR (Author)
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Composto eterociclico in cui il benzene è fuso con l'anello pirrolico. È stato identificato per la prima volta da Baeyer nel 1866 durante una ricerca sulla struttura del colorante naturale indaco.

Il farmacoforo dell'indolo è un costituente ubiquitario di molti prodotti naturali, tra cui ormoni vegetali (acido indolo-3-acetico), alcuni ormoni animali come la melatonina e la serotonina e molti alcaloidi, tra cui vinblastina, vincristina, vindesina, vinorelbina, ajmalina e fisostigmina. È anche il componente principale di diversi farmaci di sintesi come l'indometacina, la fluvastatina, lo zafirlukast e l'ondansetron.

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