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Granulomatose séptica crónica em crianças

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Book Details
Language
Portuguese
Publishers
Edições Nosso Conhecimento (29 April 2024)
Weight
0.09 KG
Publication Date
29/04/2024
ISBN-10
620749279X
Pages
56 pages
ISBN-13
9786207492794
Dimensions
15 x 0.33 x 22 cm
SKU
9786207492794
Author Name
Roeya Kolsi (Author)
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A granulomatose séptica crónica é uma imunodeficiência genética rara que resulta da disfunção do complexo nicotinamida adenina dinucleótido fosfato oxidase (NADPH oxidase) nas células fagocíticas. As manifestações clínicas são classificadas em duas categorias principais: infecciosas e inflamatórias.

As infecções são as manifestações mais comuns da doença em qualquer idade, enquanto os estados inflamatórios estão geralmente confinados aos adultos. Trata-se de uma doença grave.

O tratamento baseia-se principalmente em medidas de higiene alimentar e na quimioprofilaxia para prevenir infecções fúngicas e bacterianas. A esperança de vida melhorou significativamente, mas o prognóstico pode ser comprometido por complicações infecciosas e inflamatórias.

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