Science, Nature & Maths      Biological Sciences

Genótipos AKAP lbc e implicações para a investigação sobre GVH: GenótiposAKAP lbc e impacto na investigação de GVH em receptores de transplante de células estaminais hematopoiéticas

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Book Details
Language
Portuguese
Publishers
Edições Nosso Conhecimento (12 Jun. 2024)
Weight
0.11 KG
Publication Date
12/06/2024
ISBN-10
6207656768
Pages
68 pages
ISBN-13
9786207656769
Dimensions
15 x 0.41 x 22 cm
SKU
9786207656769
Author Name
Rahma SAID (Author)
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Este estudo utiliza a técnica PCR-SSP para avaliar a distribuição alélica e genotípica do gene AKAP lbc, que codifica os antigénios HA-3, na população tunisina. O alelo predominante, HA-3C, representa 90% da frequência deste antigénio.

O genótipo mais frequente é o homozigótico HA-3C/HA-3C (80%), seguido do heterozigótico HA-3T/HA-3*C (20%). Estes resultados fundamentais servirão de base de dados para estudos futuros que examinem a associação entre a ocorrência de GVHD e os antigénios de histocompatibilidade menor HA-3 em tunisinos que tenham sido submetidos a transplante de células estaminais hematopoiéticas.

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