Science, Nature & Maths      Biological Sciences

Genotipi AKAP lbc e implicazioni per la ricerca sulla GVH: GenotipiAKAP lbc e impatto sulla ricerca della GVH nei riceventi di trapianto di cellule staminali ematopoietiche

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Book Details
Language
Italian
Publishers
Edizioni Sapienza (12 Jun. 2024)
Weight
0.11 KG
Publication Date
12/06/2024
ISBN-10
620765675X
Pages
68 pages
ISBN-13
9786207656752
Dimensions
15 x 0.41 x 22 cm
SKU
9786207656752
Author Name
Rahma SAID (Author)
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Questo studio utilizza la tecnica PCR-SSP per valutare la distribuzione allelica e genotipica del gene AKAP lbc, che codifica per l'antigene HA-3, nella popolazione tunisina. L'allele predominante, HA-3C, rappresenta il 90% della frequenza per questo antigene.

Il genotipo più frequente è l'omozigote HA-3C/HA-3C (80%), seguito dall'eterozigote HA-3T/HA-3*C (20%). Questi risultati fondamentali serviranno come base per studi futuri che esaminino l'associazione tra l'insorgenza di GVHD e gli antigeni minori di istocompatibilità HA-3 nei tunisini sottoposti a trapianto di cellule staminali ematopoietiche.

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