Formulation and Evaluation of Nifidipine capsule by Liquisolid compact: (Novel approach for Drug Delivery)
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They may improve the active ingredients' bioavailability and readily dissolve in the digestive tract's gastric juices. The calcium-channel blocker nifedipine is frequently used to treat systemic hypertension and angina pectoris.
Nifedipine has a relatively short half-life of two hours and is completely soluble in water. As a result, it is generally acknowledged that the most effective form of Nifedipine for routine hypertension treatment is in capsule form.
The primary goal of the research was to create and assess a hard gelatin capsule dosage form of nifedipine, which is used to treat hypertension. To improve the solubility of the medication, polymers like Transcutol and PEG 400 were used.
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