Evaluation of gingival collagen in rats immunosuppressed with CsA: Evaluation of gingival collagen in experimental periodontitis in rats immunosuppressed with CsA
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The aim of this study was to compare gingival connective tissue in experimental periodontitis in rats immunosuppressed with CsA. Twenty-eight male rats (Wistar) were used, 14 treated with daily doses of 10mg/kg of CsA and 14 treated with NaCl.
After 60 days, a ligature was inserted around the 2nd upper right molar, maintained for 7 days and then 14 days to induce experimental periodontitis (T), with the contralateral molar as a control (C). After sacrificing the animals, the jaws were processed for histological analysis and 5 semi-serial sections per specimen were stained with picrosirious to quantify the collagen.
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£27.18
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£10.58
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