Estudo dos genes da beta-lactamase OXA em Acinetobacter baumannii
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No Iraque, há pouca atenção sobre a base molecular dos isolados de A. baumannii multirresistentes nos nossos hospitais, pelo que os objectivos do estudo são Investigar a distribuição de estirpes de A.
baumannii resistentes a múltiplos fármacos (MDR) isoladas de doentes internados e pesquisar a presença de genes de β-lactamases de classe D (genes blaOXA-23-Like, blaOXA-24-Like, blaOXA-51-Like e blaOXA-58-Like) em isolados de A. baumannii e investigar a sua distribuição entre todos os isolados clínicos.
Analisar a sequência dos genes blaOXA a fim de detetar as variações dos isolados locais. A correlação de genes de bombas de efluxo com a resistência a múltiplos fármacos e carbapenemes.
Medição da expressão genética dos genes blaOXA mais prevalentes. .
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£27.18
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