Science, Nature & Maths      Chemistry

Das neuartige 1,2,3-Triazol mit der Bezeichnung 5-[(1H-Indol-3yl)methylen]pyrimidin: Heterozyklische Verbindungen

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Book Details
Language
German
Publishers
Verlag Unser Wissen (30 Jun. 2024)
Weight
0.13 KG
Publication Date
30/06/2024
ISBN-10
6207741765
Pages
76 pages
ISBN-13
9786207741762
Dimensions
15 x 0.46 x 22 cm
SKU
9786207741762
Author Name
B.ASHOK KUMAR (Author)
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Heterozyklische Verbindung, bei der Benzol mit einem Pyrrolring verschmolzen ist. Es wurde erstmals 1866 von Baeyer bei der Erforschung der Struktur des natürlichen Farbstoffs Indigo identifiziert.

Das Indol-Pharmakophor ist ein allgegenwärtiger Bestandteil vieler Naturprodukte, darunter Pflanzenhormone (Indol-3-Essigsäure), einige tierische Hormone wie Melatonin und Serotonin und viele Alkaloide wie Vinblastin, Vincristin, Vindesin, Vinorelbin, Ajmalin und Physostigmin. Ebenso ist es Hauptbestandteil mehrerer synthetischer Arzneimittel wie Indomethacin, Fluvastatin, Zafirlukast und Ondansetron.

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