Cytomegalovirus and Breast Cancer: Association between CMV and proto-oncogenes in Breast cancer
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A blood sample and formalin-fixed paraffin embedded tissue block with histopathological report were obtained by a pathologist from each woman included in this study, according to ethical approval. The practical part of this study was designed around two main pathways.
First, serological detection of anti-HCMV IgG and IgM was performed using the ELISA technique. Second, Immunohistochemically technique to demonstrate the expression of HCMV early and late antigens as well as HER2 expression in malignant, benign and normal breast tissues.
These findings are the first to demonstrate the correlation between Human cytomegalovirus early and late antigens with Her2/neu overexpression in breast cancer. .
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£27.18
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