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Correlazione in vitro e in vivo di paracetamolo e tramadolo su conigli

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Book Details
Language
Italian
Publishers
Edizioni Sapienza (12 April 2024)
Weight
0.15 KG
Publication Date
12/04/2024
ISBN-10
6207378369
Pages
92 pages
ISBN-13
9786207378364
Dimensions
15 x 0.53 x 22 cm
SKU
9786207378364
Author Name
Bharatbhusan Sahu (Author)
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Lo scopo del presente studio è quello di eseguire una correlazione invitro - invivo per la formulazione contenente paracetamolo e tramadolo. Per effettuare la correlazione invitro - invivo è necessario un metodo bioanalitico HPLC convalidato.

Pertanto, è necessario sviluppare e validare un metodo HPLC nel plasma. Per condurre la correlazione invitro - invivo sono necessarie formulazioni con 3 diverse velocità di rilascio.

Queste formulazioni saranno sottoposte al tasso di dissoluzione invitro e alla biodisponibilità invivo. Quindi verrà stabilita una correlazione.

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