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Corrélation in vitro - in vivo entre le paracétamol et le tramadol chez le lapin

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Book Details
Language
French
Publishers
Editions Notre Savoir (12 April 2024)
Weight
0.15 KG
Publication Date
12/04/2024
ISBN-10
6207378350
Pages
92 pages
ISBN-13
9786207378357
Dimensions
15 x 0.53 x 22 cm
SKU
9786207378357
Author Name
Bharatbhusan Sahu (Author)
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L'objectif de cette étude est de réaliser une corrélation invitro - invivo pour la formulation contenant du paracétamol et du tramadol. Pour effectuer une corrélation invitro - invivo, une méthode HPLC bioanalytique validée est nécessaire.

Par conséquent, une méthode HPLC doit être développée et validée dans le plasma. Pour réaliser la corrélation invitro - invivo, il faut des formulations avec 3 taux de libération différents.

Ces formulations seront soumises à la vitesse de dissolution invitro et à la biodisponibilité invivo. Une corrélation sera donc établie.

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