Correlação In Vitro - In Vivo de Paracetamol e Tramadol em Coelhos
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Por conseguinte, deve ser desenvolvido e validado um método de HPLC no plasma. Para realizar a correlação invitro-invivo, são necessárias formulações com 3 taxas de libertação diferentes.
Estas formulações serão sujeitas a uma taxa de dissolução invitro e a uma biodisponibilidade invivo. Por conseguinte, será estabelecida uma correlação.
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£27.18
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