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Chronic septic granulomatosis in children

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Book Details
Language
English
Publishers
Our Knowledge Publishing (29 April 2024)
Weight
0.09 KG
Publication Date
29/04/2024
ISBN-10
6207492765
Pages
56 pages
ISBN-13
9786207492763
Dimensions
15 x 0.33 x 22 cm
SKU
9786207492763
Author Name
Roeya Kolsi (Author)
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Chronic septic granulomatosis is a rare genetic immune deficiency resulting from dysfunction of the nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase) complex in phagocytic cells. Clinical manifestations fall into two broad categories: infectious and inflammatory.

Infections are the most common manifestations of the disease at any age, while inflammatory conditions are usually confined to adults. This is a serious disease.

Management is mainly based on hygienic-dietary measures and chemo-prophylaxis to prevent fungal and bacterial infections. Life expectancy has improved markedly, but the prognosis may be jeopardized by infectious and inflammatory complications.

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