Chronic lymphocytic leukaemia:: new diagnostic and therapeutic advances
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Diagnosis is based mainly on B hyperlymphocytosis > 5G/L persisting for more than three months, a blood smear and immunophenotyping of blood cells. Other tests, such as del 17 p +/- Tp 53, IgHV mutation status, CD 38, etc.
, are of interest in characterising predictive prognostic factors in order to better identify patients at risk of progression and choose the appropriate therapeutic strategy. This haemopathy generally has a good prognosis, but the course is very heterogeneous, with the majority of asymptomatic patients having a survival similar to that of healthy subjects of the same age and sex.
On the other hand, some patients have a progressive disease, with an increase in adenopathies and worsening cytopenias, requiring specific treatment. .
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£27.18
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