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Son histoire naturelle est la plus étudiée au monde et il en est ressorti une indication de dépistage qui a permis dans les pays développés de faire regresser le taux de mortalité, ceci étant aussi associé à l’amélioration des traitements proposés. Sa prise en charge doit absolument être multidisciplinaire.
Il n’y a pas de cancer humain dont l’expression clinique soit aussi variable et l’évolution aussi imprévisible que celle des cancers du sein. L’événement le plus important est la survenue des métastases qui signe la dissémination à distance et compromet gravement le pronostic vital.
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