Biologia Molecular e Celular: Investigação do papel do HDAC1 numa linha celular de cancro da mama através da adaptação do CRISPR-CAS como técnica de edição de genes
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Um exemplo deste gene é o gene HDAC1, que é uma proteína multifuncional e desempenha um papel na regulação da expressão genética . Utilizando o sistema CRISPR/Cas9, uma notável abordagem de edição de genesedição de genes essencial na identificação e validação de alvos genómicos com potencialpotencial tumoricida, foi investigado o papel da HDAC1 numa linha celular de cancro da mamacancro da mama, MCF-7.
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