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Biologia molecolare patologica dell'infezione da Coronavirus SARS-CoV-2

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Book Details
Language
Italian
Publishers
Edizioni Sapienza (5 May 2024)
Weight
0.14 KG
Publication Date
05/05/2024
ISBN-10
6207511123
Pages
88 pages
ISBN-13
9786207511129
Dimensions
15 x 0.51 x 22 cm
SKU
9786207511129
Author Name
Ilie Vasiliev (Author)
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I coronavirus sono una famiglia di virus a RNA che infettano l'uomo e altri mammiferi, uccelli e anfibi. Il genoma del virus è costituito da RNA positivo a singolo filamento, che codifica nucleoproteina, proteina di membrana, proteina dell'envelope, glicoproteina spike e polimerasi.

I coronavirus sono caratterizzati dalla glicoproteina S, dalle proteine transmembrana M ed E e dalla nucleoproteina che si combina con l'RNA virale per formare un complesso ribonucleoproteico virale. La proteina di membrana del coronavirus della sindrome respiratoria acuta grave di tipo 2 (SARS-CoV-2) è una proteina strutturale glicosilata che si localizza nel reticolo endoplasmatico e nel Golgi ed è essenziale per l'assemblaggio delle particelle virali.

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