Auswirkungen eines BMP-Antagonisten auf die Frakturheilung in einem Mausmodell
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Jüngste Studien haben gezeigt, dass RAP-661, ein Antagonist der Knochenmorphogenetischen Proteine (BMP) 2 und BMP-4, der an seinen Rezeptor BMPR-1A bindet, eine anabole Wirksamkeit bei der Behandlung des mit Osteoporose verbundenen Knochenverlusts aufweist. Ziel dieser Studie war es, die Wirksamkeit des Proteins RAP-661 als therapeutisches Mittel zur Verbesserung der Frakturheilung zu bewerten.
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