Anwendungen des aus Blutplättchen gewonnenen Wachstumsfaktors in der Parodontologie
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In den letzten Jahren wurde gereinigter rekombinanter humaner PDGF (rh-PDGF) in Kombination mit synthetischen Matrizen wie Beta-Tricalciumphosphat (β-TCP) oder Allotransplantaten untersucht, um die parodontale Regeneration bei infraalem Defekt und Gingivarezessionsdefekten in einer Reihe strenger klinischer und präklinischer Studien zu erreichen, die vielversprechende Ergebnisse brachten. Diese evidenzbasierten Ergebnisse werden hier zusammengefasst, und es wird erörtert, inwieweit diese Therapie zum neuen Standard für die Behandlung bestimmter Arten von Knochen- und Weichgewebedefekten werden könnte.
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