Altérations du foie pendant la chimiothérapie: Entretien de la leucémie lymphoïde aiguë
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L'origine de cette maladie est encore inconnue, mais elle est associée à des facteurs génétiques et environnementaux tels que l'exposition aux radiations ionisantes, aux agents chimiques et aux agents alkylants. C'est la maladie maligne la plus fréquente chez l'enfant (80 % de toutes les leucémies de l'enfant) avec une incidence annuelle de 2 à 3 cas pour 100 000 enfants.
L'hépatotoxicité est une cause fréquente d'arrêt du traitement dans la phase d'entretien de la leucémie lymphoïde aiguë. Cet arrêt du traitement augmente la probabilité de rechute hématologique jusqu'à 10 %.
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£27.18
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