Science, Nature & Maths      Biological Sciences

AKAP lbc genotypes and implications for GVH research: AKAP lbc Genotypes and Impact on GVH Research in Hematopoietic Stem Cell Transplant Recipients

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Book Details
Language
English
Publishers
Our Knowledge Publishing (12 Jun. 2024)
Weight
0.11 KG
Publication Date
12/06/2024
ISBN-10
6207656733
Pages
64 pages
ISBN-13
9786207656738
Dimensions
15 x 0.38 x 22 cm
SKU
9786207656738
Author Name
Rahma SAID (Author)
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This study uses the PCR-SSP technique to assess the allelic and genotypic distribution of the AKAP lbc gene, coding for HA-3 antigens, in the Tunisian population. The predominant allele, HA-3C, represents 90% of the frequency for this antigen.

The most frequent genotype is homozygous HA-3C/HA-3C (80%), followed by heterozygous HA-3T/HA-3*C (20%). These fundamental results will serve as a database for future studies examining the association between the occurrence of GVHD and HA-3 minor histocompatibility antigens in Tunisian hematopoietic stem cell transplant recipients.

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