Acute tubulointerstitial nephritis and uveitis syndrome (TINU): about 6 cases and review of the literature

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Book Details
Language
English
Publishers
Our Knowledge Publishing (2 Aug. 2024)
Weight
0.19 KG
Publication Date
02/08/2024
ISBN-10
6207909658
Pages
120 pages
ISBN-13
9786207909650
Dimensions
15.24 x 0.71 x 22.86 cm
SKU
9786207909650
Author Name
Abir Derbel (Author)
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Tubular and interstitial nephropathy with uveitis (NITU ) syndrome is a rare oculo-renal disorder. We will describe the clinical and biological aspects of this entity.

Our study was retrospective from 1996 to 2024. All patients had histologically proven interstitial renal involvement and ocular involvement.

Six patients were included, including 5 women and 1 man with an average age of 39. Ocular involvement was inaugural in 4 cases and concomitant with renal involvement in 2.

Ophthalmological examination revealed anterior and intermediate uveitis in 3 cases each. Biological inflammatory syndrome and renal failure were constant.

Urinalysis revealed mild proteinuria with aseptic leukocyturia in 4 cases each; microscopic hematuria in 2 cases and glycosuria without diabetes. Corticosteroids (1mg/Kg/day) were prescribed with boluses of methylprednisolone, mydriatic eye drops and cortcoide eye drop for uveitis.

General corticosteroid therapy was discontinued in 5 cases and maintained in 1. .

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